As designers move upstream from traditional product and service design to engage with challenges characterised by complexity, uniqueness, value conflict, Lactoferrin and ambiguity over objectives, they have increasingly integrated systems approaches into their practice.This synthesis of systems thinking with design thinking is forming a distinct ne
Dual-Channel Green Supply Chain Decision-Making and Coordination considering CSR and Consumer Green Preferences
With the rapid development of the Internet and changes in consumer buying habits, many manufacturers are increasingly relying COCONUT REISHI DEODORANT on online channels to sell their products as opposed to traditional retail channels.In this study, we innovatively investigate the impact of corporate social responsibility (CSR) and consumer green p
What Can We Learn from Single Sarcomere and Myofibril Preparations?
Sarcomeres are the smallest functional contractile unit of muscle, and myofibrils are striated muscle organelles that are comprised of sarcomeres that are strictly aligned in series.Furthermore, passive forces in sarcomeres and myofibrils are almost exclusively produced by the structural protein titin, and all contractile, regulatory, and structura
Therapeutic Genome Editing in Cardiovascular Diseases
Summary: A variety of genetic cardiovascular diseases may one day be curable using gene editing technology.Germline genome editing and correction promises to permanently remove monogenic cardiovascular disorders from the offspring and subsequent generations of affected families.Although technically feasible and likely to be ready for implementation
Synergistic effects of bacteriophage cocktail and antibiotics combinations against extensively drug-resistant Acinetobacter baumannii
Abstract Background The extensively drug-resistant (XDR) strains of Acinetobacter baumannii have become a major cause of nosocomial infections, increasing morbidity and mortality worldwide.Many different treatments, including phage therapy, are attractive ways to overcome the challenges of antibiotic resistance.Methods This study investigates the b